The Future of Biology Is Agentic
Hosted with ClawBio — bioinformatics-native AI agent skills.
The pitch
Bioinformatics is moving from scripts you babysit to skills your agent calls. ClawBio packages reproducible bioinformatics workflows — pharmacogenomics, drug-photo lookup, ClinPGx queries — as agent-callable skills that run locally and never leak your data. In this session we'll install ClawBio, run a real pharmacogenomics report end-to-end on demo genetic data, and watch an agent interpret CYP2D6 metabolizer status against CPIC drug guidelines.
Core idea: a VCF (or 23andMe / AncestryDNA file) goes in, a publication-grade pharmacogenomics report comes out — calls star alleles, assigns metabolizer phenotypes, and lists CPIC-backed dosage recommendations for 51 drugs across 12 genes. All in under a second, on your laptop.
The plan
60 min · 5 phasesgit clone + pip install. Both routes work.pharmgx --demo. Inspect the generated report, figures, and reproducibility bundle.pharmgx into a multi-step skill: ingest patient file → call ClawBio → render a clinician-friendly summary card.Full walkthrough: tutorials/11-pharmacogenomics.
30-second taste
If you want to try it before the workshop, this is the whole demo:
# Option A — Claude Code plugin /plugin marketplace add ClawBio/ClawBio /plugin install clawbio # Option B — local install git clone https://github.com/ClawBio/ClawBio.git && cd ClawBio pip install -r requirements.txt python clawbio.py run pharmgx --demo
The --demo flag ships with synthetic genotypes so you can see the full report without bringing your own data. Bring a 23andMe or AncestryDNA file if you want to run it on yourself — your data stays on your laptop.
Bring this
- Laptop with macOS, Windows, or Linux. Admin rights to install Python packages.
- Python 3.10+ (or Claude Code with the plugin marketplace enabled — either works).
- Optional: a 23andMe
.txt, AncestryDNA.csv, or VCF file you'd like to analyse on yourself.
No prior bioinformatics experience needed. If you've never written a VCF parser, that's the point — the skill does it for you. See Setup if you haven't installed an agent yet.