Bug fixes

  • get_color_map
    • Fix color_vector assignment.

Bug fixes

  • Tests
    • Use force_new=TRUE where some tests occasionally fail with cached files.
    • test-load_example_results: Update test files.
    • test-prioritise_targets: Remove unused arguments and change input size.
    • test-prioritise_targets_network: Process top_targets to include effect
    • test-plot_differential_outcomes: Use non-specific plot name in patchwork::wrap_plots.
    • test-plot_differential_outcomes: Wrap p3 in expect_error to prevent test failure even if error was handled.
    • test-report_plot: Fix detection for ggplot object. variable.
  • Vignettes
    • MSTExplorer: Update effect variable to fold_change.
  • add_logfc
    • Return results with new column rather than directly modifying the original input.
    • Update references (add_logfc(results) -> results <- add_logfc(results)).
  • ttd_check, plot_differential_outcomes, prioritise_targets_grid
  • plot_ttd
    • Remove fill aesthetic for geom_text (doesn’t exist anymore).
  • extract_help
    • [DEVELOPEMENT ONLY] Look for help docs only in legitimate pkg installation paths.
  • subset_results
    • Add new effect_var argument.
    • Adjust default effect_threshold to 0.1.
  • add_symptom_results
    • Only merge results and phenotypes_to_genes if required (prevents column duplicates with altered names).
  • map_tissue
    • Rewrite merge logic to fix error: attempt to replicate non-vector.
  • test_target_celltypes
    • Uncomment add_ancestors(results) to ensure required ancestor columns are present.
  • Add missing import: simona

New features

  • run_phenomix: can now take multiple annotLevels at once (will iterate).

New features

  • add function run_congenital_enrichment
  • add function plot_celltype_severity

New features

  • add function prioritise_targets_grid

Bug fixes

  • plot_bar_dendro_facets
    • Add hpo arg to pass HPO directly.
    • Fix data_summary so that denominator is the number of on-target cell types only.

New features

  • Rename MSTExplorer.
  • Revamp to work with KGExplorer.